Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphisms of 17 β-hydroxysteroid dehydrogenase 3 and the risk of hypospadias.

The journal of sexual medicine - 1 Aug 2010

Sata Fumihiro, Kurahashi Norie, Ban Susumu, Moriya Kimihiko, Tanaka Kazuyuki D, Ishizuka Mayumi, Nakao Hiroyuki, Yahata Yuichiro, Imai Hirohisa, Kakizaki Hidehiro, Nonomura Katsuya, Kishi Reiko

Abstract excerpt

INTRODUCTION: Hypospadias is a common congenital anomaly caused by incomplete fusion of urethral folds. Development of the urethra and external genital system in the male fetus is an androgen-dependent process. In this regard, enzymes 17 β-hydroxysteroid dehydrogenase type 3 (17 β HSD3, encoded by HSD17B3) and steroid 5 α-reductase type 2 (encoded by SRD5A2) play crucial roles. AIM: To investigate the possible...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 17-Hydroxysteroid Dehydrogenases
Share to 3-Oxo-5-alpha-Steroid 4-Dehydrogenase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Carrier Screening

Share to Homozygote

Share to Hypospadias

Share to Infant, Newborn

Share to Membrane Proteins

Source

Identifiers

PMID: 20059664
DOI: 10.1111/j.1743-6109.2009.01641.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphisms of 17 β-hydroxysteroid dehydrogenase 3 and the risk of hypospadias.PMID 20059664Read ↗

Steroid 5-alpha-reductase type 2 (SRD5A2) gene V89L polymorphism and hypospadias risk: A meta-analysis.Semantic proximity Read ↗

Association of SRD5A2 gene mutations with risk of hypospadias in the Iranian population.Semantic proximity Read ↗

The valine allele of the V89L polymorphism in the 5-alpha-reductase gene confers a reduced risk for hypospadias.Semantic proximity Read ↗

Hypospadias and variants in genes related to sex hormone biosynthesis and metabolism.Semantic proximity Read ↗

Genotype-phenotype correlation and identification of two novel SRD5A2 mutations in 33 Chinese patients with hypospadias.Semantic proximity Read ↗

Aetiology of hypospadias: a systematic review of genes and environment.Semantic proximity Read ↗

Association of a tagging single nucleotide polymorphism in the androgen receptor gene region with susceptibility to severe hypospadias in a Caucasian population.Semantic proximity Read ↗

Molecular epidemiology of hypospadias: review of genetic and environmental risk factors.Semantic proximity Read ↗

Genetics of hypospadias: are single-nucleotide polymorphisms in SRD5A2, ESR1, ESR2, and ATF3 really associated with the malformation?Semantic proximity Read ↗

Mutation analysis of the SRD5A2, AR and SF-1 genes in 52 Chinese boys with hypospadias.Semantic proximity Read ↗

Genetic Polymorphism in the RYR1 C6487T Is Associated with Severity of Hypospadias in Chinese Han Children.Semantic proximity Read ↗

Prevalence and possible causes of hypospadiasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.