Article
Exposure to environmental level phenanthrene induces a NASH-like phenotype in new born rat.
Environmental pollution (Barking, Essex : 1987) - 1 Aug 2018
Guo Jiaojiao, Wang Chonggang, Guo Zhizhun, Zuo Zhenghong
Abstract excerpt
More and more evidence indicates that persistent organic pollutants (POPs) are a risk factor for non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). Phenanthrene (Phe) is a kind of POP which existed extensively in the environment, but whose toxicity on mammals has so far received less focus. Subcutaneously injection of Phe (0.5, 5, 50 μg/kg) for 21 days induced significant...
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