Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Successful treatment with interleukin-17A antagonists of generalized pustular psoriasis in patients without IL36RN mutations.

The Journal of dermatology - 1 Jul 2018

Wilsmann-Theis Dagmar, Schnell Lisa Marie, Ralser-Isselstein Veronika, Bieber Thomas, Schön Michael P, Hüffmeier Ulrike, Mössner Rotraut

Abstract excerpt

Generalized pustular psoriasis (GPP) is a potentially life-threatening disease that can be attributed to mutations in IL36RN in a subgroup of patients. In small trials, interleukin (IL)-17A and IL-17RA antagonists have been shown to be effective in patients with generalized pustular psoriasis in Japan. We identified seven patients who received the IL-17A antagonists secukinumab (six cases) or ixekizumab (one...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to Antibodies, Monoclonal, Humanized

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dermatologic Agents

Share to Interleukin-17

Share to Interleukins

Share to Psoriasis

Share to Treatment Outcome

Source

Identifiers

PMID: 29655177
DOI: 10.1111/1346-8138.14318

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Successful treatment with interleukin-17A antagonists of generalized pustular psoriasis in patients without IL36RN mutations.PMID 29655177Read ↗

Successful treatment of a 3-year-old girl with generalized pustular psoriasis using secukinumab monotherapy.Semantic proximity Read ↗

Therapeutic Efficacy of Interleukin 12/Interleukin 23 Blockade in Generalized Pustular Psoriasis Regardless of IL36RN Mutation Status.Semantic proximity Read ↗

Spesolimab for generalized pustular psoriasis: a prospective study with a 6-month follow-up.Semantic proximity Read ↗

The majority of generalized pustular psoriasis without psoriasis vulgaris is caused by deficiency of interleukin-36 receptor antagonist.Semantic proximity Read ↗

Mutation analysis of the IL36RN gene in 14 Japanese patients with generalized pustular psoriasis.Semantic proximity Read ↗

Generalized pustular psoriasis: immunological mechanisms, genetics, and emerging therapeutics.Semantic proximity Read ↗

Successful therapy with anakinra in a patient with generalized pustular psoriasis carrying IL36RN mutations.Semantic proximity Read ↗

An update on genetic basis of generalized pustular psoriasis (Review).Semantic proximity Read ↗

A novel IL36RN/IL1F5 homozygous nonsense mutation, p.Arg10X, in a Japanese patient with adult-onset generalized pustular psoriasisSemantic proximity Read ↗

Generalized pustular psoriasis-like drug eruption manifested by systemic glucocorticosteroid in a patient without IL36RN mutation or an immunological disorder.Semantic proximity Read ↗

Mutation analysis of the IL36RN gene in Chinese patients with generalized pustular psoriasis with/without psoriasis vulgaris.Semantic proximity Read ↗

Clinical advances in biological therapy for generalized pustular psoriasis: a review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.