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Article

Phenotypic characterization of the SIRC (Statens Seruminstitut Rabbit Cornea) cell line reveals a mixed epithelial and fibroblastic nature.

Experimental eye research - 1 Jul 2018

Olivieri Melania, Cristaldi Martina, Pezzino Salvatore, Rusciano Dario, Tomasello Barbara, Anfuso Carmelina Daniela, Lupo Gabriella

Abstract excerpt

The aim of the present study was to investigate, in the Statens Seruminstitut Rabbit Cornea (SIRC) cell line, the presence of epithelial and fibroblastic markers, comparing their levels with those of the human Retinal Pigmented Epithelial (ARPE-19) cell line, and the Human Keratocyte (HK) cell line, respectively. SIRC cells, often described as of epithelial origin, are used as a corneal epithelial barrier model...

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PMID: 29653143
DOI: 10.1016/j.exer.2018.04.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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