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Article

Isolation, Characterization, and Establishment of Spontaneously Immortalized Cell Line HRPE-2S With Stem Cell Properties.

Journal of cellular physiology - 1 Oct 2017

Shams Najafabadi Hoda, Soheili Zahra-Soheila, Samiei Shahram, Ahmadieh Hamid, Ranaei Pirmardan Ehsan, Masoumi Maryam

Abstract excerpt

The retinal pigment epithelium is a monolayer of highly specialized pigmented cells located between the neural retina and the Bruch's membrane of the choroid. RPE cells play a crucial role in the maintenance and function of the underlying photoreceptors. This study introduces a spontaneously arising human retinal pigment epithelial cell line, HRPE-2S, which was isolated from primary RPE cell culture of 2 days old...

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Source

Identifiers

PMID: 27943290
DOI: 10.1002/jcp.25729

Genes

RPE
PAX6
RPE65
SOX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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