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Article

Spontaneous acquisition of infinite proliferative capacity by a rabbit corneal endothelial cell line with maintenance of phenotypic and physiological characteristics.

Journal of tissue engineering and regenerative medicine - 1 Apr 2017

Kageyama Tomofumi, Hayashi Ryuhei, Hara Susumu, Yoshikawa Kenichi, Ishikawa Yuki, Yamato Masayuki, Nishida Kohji

Abstract excerpt

Rabbit cells and models are frequently used in pharmacological experiments and toxicity tests and are particularly useful for corneal transplant experiments. Here, we obtained a corneal endothelial cell line from normal rabbit corneal endothelium that had acquired infinite proliferative potential without requiring gene transfer. These infinitely proliferative rabbit corneal endothelial cells (iRCECs) could be...

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PMID: 25758102
DOI: 10.1002/term.2005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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