Article
A Single Amino Acid in the Polymerase Acidic Protein Determines the Pathogenicity of Influenza B Viruses.
Journal of virology - 1 Jul 2018
Bae Joon-Yong, Lee Ilseob, Kim Jin Il, Park Sehee, Yoo Kirim, Park Miso, Kim Gayeong, Park Mee Sook, Lee Joo-Yeon, Kang Chun, Kim Kisoon, Park Man-Seong
Abstract excerpt
Influenza B virus (IBV) is one of the human respiratory viruses and one of the targets of seasonal vaccination. However, the bifurcation of two antigenically distinct lineages of IBVs makes it difficult to arrange proper medical countermeasures. Moreover, compared with pathogenicity-related molecular markers known for influenza A virus, little has been known for IBVs. To understand pathogenicity caused by IBVs,...
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