Article
CoERG11 A395T mutation confers azole resistance in Candida orthopsilosis clinical isolates.
The Journal of antimicrobial chemotherapy - 1 Jul 2018
Rizzato Cosmeri, Poma Noemi, Zoppo Marina, Posteraro Brunella, Mello Enrica, Bottai Daria, Lupetti Antonella, Sanguinetti Maurizio, Tavanti Arianna
Abstract excerpt
Background: Candida orthopsilosis is a human fungal pathogen responsible for a wide spectrum of symptomatic infections. Evidence suggests that C. orthopsilosis is mainly susceptible to azoles, the most extensively used antifungals for treatment of these infections. However, fluconazole-resistant clinical isolates are reported. Objectives: This study evaluated the contribution of a single amino acid substitution...
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