Article
Molecular analysis of hepatitis B virus associated with vaccine failure in infants and mothers: a case-control study in Thailand.
Journal of medical virology - 1 Aug 2012
Sa-Nguanmoo Pattaratida, Tangkijvanich Pisit, Tharmaphornpilas Piyanit, Rasdjarmrearnsook Aim-Orn, Plianpanich Saowanee, Thawornsuk Nutchanart, Theamboonlers Apiradee, Poovorawan Yong
Abstract excerpt
Perinatal transmission of hepatitis B virus (HBV) has been controlled incompletely despite adequate immunoprophylaxis in infants. The aim of this study was to characterize virological factors of HBV associated with vaccine failure in Thailand. Sera of 14 infected infants (13 HBeAg-positive and one HBeAg-negative) with vaccine failure and their respective mothers (group M1) were tested quantitatively for HBV DNA...
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