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Article

Inorganic phosphorus (Pi) in CSF is a biomarker for SLC20A2-associated idiopathic basal ganglia calcification (IBGC1).

Journal of the neurological sciences - 15 May 2018

Hozumi Isao, Kurita Hisaka, Ozawa Kazuhiro, Furuta Nobuyuki, Inden Masatoshi, Sekine Shin-Ichiro, Yamada Megumi, Hayashi Yuichi, Kimura Akio, Inuzuka Takashi, Seishima Mitsuru

Abstract excerpt

INTRODUCTION: Idiopathic basal ganglia calcification (IBGC), also called Fahr's disease or recently primary familial brain calcification (PFBC), is characterized by abnormal deposits of minerals including calcium mainly and phosphate in the brain. Mutations in SLC20A2 (IBGC1 (merged with former IBGC2 and IBGC3)), which encodes PiT-2, a phosphate transporter, is the major cause of IBGC. Recently, Slc20a2-KO mice...

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PMID: 29627011
DOI: 10.1016/j.jns.2018.03.014

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PDGFB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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