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Article

Slc20a2 is critical for maintaining a physiologic inorganic phosphate level in cerebrospinal fluid.

Neurogenetics - 1 Apr 2016

Jensen Nina, Autzen Jacob Kwasi, Pedersen Lene

Abstract excerpt

Mutations in the SLC20A2-gene encoding the inorganic phosphate (Pi) transporter PiT2 can explain approximately 40% of the familial cases of the rare neurodegenerative disorder primary familial brain calcification (Fahr's disease). The disease characteristic, cerebrovascular-associated calcifications, is also present in Slc20a2-knockout (KO) mice. Little is known about the specific role(s) of PiT2 in the brain....

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Identifiers

PMID: 26660102
DOI: 10.1007/s10048-015-0469-6
PMCID: PMC4794525

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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