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Article

Golgi damage caused by dysfunction of PiT-2 in primary familial brain calcification.

Biochemical and biophysical research communications - 29 Jan 2023

Sun Huifang, Wang Zhuoya, Zhang Qi, Chen Na, Tang Mibo, Yang Zhihua, Xu Yuming, Kang Jiansheng, Wang Yanlin

Abstract excerpt

The Golgi apparatus is vital for protein modification and molecular trafficking. It is essential for nerve development and activity, and damage thereof is implicated in many neurological diseases. Primary familial brain calcification (PFBC) is a rare inherited neurodegenerative disease characterized by multiple brain calcifications. SLC20A2, which encodes the inorganic phosphate transporter 2 (PiT-2) protein, is...

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Identifiers

PMID: 36584480
DOI: 10.1016/j.bbrc.2022.12.050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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