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Article

Interactions among Candidate Genes Selected by Meta-Analyses Resulting in Higher Risk of Ischemic Stroke in a Chinese Population.

PloS one - 1 Jan 2015

Luo Man, Li Jiaoxing, Sun Xunsha, Lai Rong, Wang Yufang, Xu Xiaowei, Sheng Wenli

Abstract excerpt

Ischemic stroke (IS) is a multifactorial disorder caused by both genetic and environmental factors. The combined effects of multiple susceptibility genes might result in a higher risk for IS than a single gene. Therefore, we investigated whether interactions among multiple susceptibility genes were associated with an increased risk of IS by evaluating gene polymorphisms identified in previous meta-analyses,...

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Source

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Identifiers

PMID: 26710338
DOI: 10.1371/journal.pone.0145399
PMCID: PMC4692506

Genes

ACE
APOE
FGB
MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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