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Article

Risk-reduction mastectomy: clinical issues and research needs.

Journal of the National Cancer Institute - 5 Sept 2001

Stefanek M, Hartmann L, Nelson W

Abstract excerpt

Risk-reduction mastectomy (RRM), also known as bilateral prophylactic mastectomy, is a controversial clinical option for women who are at increased risk of breast cancer. High-risk women, including women with a strong family history of breast cancer and BRCA1/2 mutation carriers, have several clinical options: risk-reduction surgery (bilateral mastectomy and bilateral oophorectomy), surveillance (mammography,...

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Source

Identifiers

PMID: 11535704
DOI: 10.1093/jnci/93.17.1297

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Risk-reduction mastectomy: clinical issues and research needs.PMID 11535704Read ↗

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Prophylactic bilateral mastectomy for breast cancer prevention.Semantic proximity Read ↗

Risk-reduction surgery decisions in high-risk women seen for genetic counseling.Semantic proximity Read ↗

Preoperative risk assessment among women undergoing bilateral prophylactic mastectomy for cancer risk reduction.Semantic proximity Read ↗

Risk-reducing mastectomy for the prevention of primary breast cancer.Semantic proximity Read ↗

Psychological implications of risk-reducing mastectomies in BRCA1/2 mutation carriers.Semantic proximity Read ↗

Immediate Psychological Implications of Risk-Reducing Mastectomies in Women With Increased Risk of Breast Cancer: A Comparative Study.Semantic proximity Read ↗

Decision-making for bilateral risk-reducing mastectomy for an increased lifetime breast cancer risk: A qualitative metasynthesis.Semantic proximity Read ↗

Breast cancer after bilateral risk-reducing mastectomy.Semantic proximity Read ↗

Prophylactic surgery to reduce breast cancer risk: a brief literature review.Semantic proximity Read ↗

The impact of prophylactic mastectomy on sexual well-being: a systematic review.Semantic proximity Read ↗

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