Article
Pancreatic cancer genomics.
Current opinion in genetics & development - 1 Feb 2014
Chang David K, Grimmond Sean M, Biankin Andrew V
Abstract excerpt
Pancreatic cancer is one of the most lethal malignancies. The overall median survival even with treatment is only 6-9 months, with almost 90% succumbing to the disease within a year of diagnosis. It is characterised by an intense desmoplastic stroma that may contribute to therapeutic resistance, and poses significant challenges for genomic sequencing studies. It is recalcitrant to almost all therapies and...
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