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Article

Targeted Gene Deletion in Cordyceps militaris Using the Split-Marker Approach.

Molecular biotechnology - 1 May 2018

Lou HaiWei, Ye ZhiWei, Yun Fan, Lin JunFang, Guo LiQiong, Chen BaiXiong, Mu ZhiXian

Abstract excerpt

The macrofungus Cordyceps militaris contains many kinds of bioactive ingredients that are regulated by functional genes, but the functions of many genes in C. militaris are still unknown. In this study, to improve the frequency of homologous integration, a genetic transformation system based on a split-marker approach was developed for the first time in C. militaris to knock out a gene encoding a terpenoid...

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Share to Alkyl and Aryl Transferases
Share to Fungal Proteins
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29605840
DOI: 10.1007/s12033-018-0080-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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