Article
Clinical and genetic risk factors for decreased bone mineral density in Japanese patients with inflammatory bowel disease.
Journal of gastroenterology and hepatology - 1 Nov 2018
Naito Takeo, Yokoyama Naonobu, Kakuta Yoichi, Ueno Kazuko, Kawai Yosuke, Onodera Motoyuki, Moroi Rintaro, Kuroha Masatake, Kanazawa Yoshitake, Kimura Tomoya, Shiga Hisashi, Endo Katsuya, Nagasaki Masao, Masamune Atsushi, Kinouchi Yoshitaka, Shimosegawa Tooru
Abstract excerpt
BACKGROUND AND AIM: Patients with inflammatory bowel disease (IBD) are at a high risk of low bone mineral density (BMD). Reportedly, clinical and genetic factors cause low BMD in Caucasians; however, studies in non-Caucasian populations remain scarce. METHODS: Clinical risk factors for low BMD were investigated in 266 Japanese patients with IBD, and a genome-wide association analysis (GWAS) was performed using...
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