Article
Low body mass not vitamin D receptor polymorphisms predict osteoporosis in patients with inflammatory bowel disease.
Alimentary pharmacology & therapeutics - 1 Apr 2008
Noble C L, McCullough J, Ho W, Lees C W, Nimmo E, Drummond H, Bear S, Hannan J, Millar C, Ralston S H, Satsangi J
Abstract excerpt
BACKGROUND: Osteoporosis is a recognized complication of inflammatory bowel disease (IBD). Aim To investigate the role of environmental factors and vitamin D receptor (VDR) variants on the prevalence of osteoporosis. METHODS: DEXA scans and case note review were performed on 440 IBD patients from 1997 to 2006. All the IBD patients and 240 healthy controls were genotyped for VDR variants Taq-1 and Apa-1 using...
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