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Mechanistic insights into staphylopine-mediated metal acquisition

26 Mar 2018

Abstract excerpt

, plays a central role in transition-metal acquisition and bacterial virulence. The StP-like biosynthesis loci are present in various pathogens, and the proteins responsible for StP/metal transportation have been determined. However, the molecular mechanisms of how StP/metal complexes are recognized and transported remain unknown. We report multiple structures of the extracytoplasmic solute-binding protein CntA...

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PMID: 29581261
DOI: 10.1073/pnas.1718382115

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