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New Insights into the Role of Zinc Acquisition and Zinc Tolerance in Group A Streptococcal Infection

22 Mar 2018

Abstract excerpt

ABSTRACT Zinc plays an important role in host innate immune function. However, the innate immune system also utilizes zinc starvation (“nutritional immunity”) to combat infections. Here, we investigate the role of zinc import and export in the protection of Streptococcus pyogenes (group A Streptococcus ; GAS), a Gram-positive bacterial pathogen responsible for a wide spectrum of human diseases, against challenge...

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PMID: 29581188
DOI: 10.1128/iai.00048-18

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