Article
Synergistic effects of rmhTRAIL and 17-AAG on the proliferation and apoptosis of multiple myeloma cells.
Hematology (Amsterdam, Netherlands) - 1 Oct 2018
Wang Jing, Li Yun, Sun Wei, Liu Jing, Chen Wenming
Abstract excerpt
OBJECTIVE: This study aimed to investigate synergistic effects of recombinant mutant human tumor necrosis factor-related apoptosis-inducing ligand (rmhTRAIL) and heat-shock protein 90 (HSP90) inhibitor (geldanamycin derivative 17 -allylamino- 17-demethoxy -geldanamycin, 17-AAG) on the proliferation and apoptosis of multiple myeloma (MM) cells. METHODS: MTT assays evaluated inhibitory effects of rmhTRAIL and...
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