Article
Circulating BRAFV600E Levels Correlate with Treatment in Patients with Thyroid Carcinoma.
Thyroid : official journal of the American Thyroid Association - 1 Mar 2018
Lubitz Carrie C, Zhan Tiannan, Gunda Viswanath, Amin Salma, Gigliotti Benjamin J, Fingeret Abbey L, Holm Tammy M, Wachtel Heather, Sadow Peter M, Wirth Lori J, Sullivan Ryan J, Panka David J, Parangi Sareh
Abstract excerpt
BACKGROUND: BRAFV600E is the most common mutation in papillary thyroid carcinoma (PTC) and can be associated with aggressive disease. Previously, a highly sensitive blood RNA-based BRAFV600E assay was reported. The objective of this study was to assess the correlation of BRAFV600E circulating tumor RNA levels with surgical and medical treatment. METHODS: Circulating BRAFV600E levels were assessed in (i) a murine...
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