Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CRISPR/Cas9 Technology as an Emerging Tool for Targeting Amyotrophic Lateral Sclerosis (ALS)

19 Mar 2018

Abstract excerpt

The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein-9 nuclease (Cas9) is a genome editing tool that has recently caught enormous attention due to its novelty, feasibility, and affordability. This system naturally functions as a defense mechanism in bacteria and has been repurposed as an RNA-guided DNA editing tool. Unlike zinc-finger nucleases (ZFNs) and transcription...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis Research
Share to CRISPR and Genetic Engineering
Share to Prion Diseases and Protein Misfolding

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29562705
DOI: 10.3390/ijms19030906

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CRISPR/Cas9 Technology as an Emerging Tool for Targeting Amyotrophic Lateral Sclerosis (ALS)PMID 29562705Read ↗

CRISPR/Cas9: implication for modeling and therapy of amyotrophic lateral sclerosisSemantic proximity Read ↗

In vivo genome editing improves motor function and extends survival in a mouse model of ALS.Semantic proximity Read ↗

Advancements in CRISPR-Based Therapies for Genetic Modulation in Neurodegenerative Disorders.Semantic proximity Read ↗

Current approaches in CRISPR-Cas9 mediated gene editing for biomedical and therapeutic applications.Semantic proximity Read ↗

Efficacy and long-term safety of CRISPR/Cas9 genome editing in the SOD1-linked mouse models of ALSSemantic proximity Read ↗

Clinical applications of the CRISPR/Cas9 genome-editing system: Delivery options and challenges in precision medicineSemantic proximity Read ↗

Development and Application of CRISPR-Cas Based ToolsSemantic proximity Read ↗

CRISPR-Cas9 for treating hereditary diseases.Semantic proximity Read ↗

Application of CRISPR/Cas9 in the management of Alzheimer’s disease and Parkinson’s disease: a reviewSemantic proximity Read ↗

Strategies to overcome the main challenges of the use of CRISPR/Cas9 as a replacement for cancer therapy.Semantic proximity Read ↗

Delivering CRISPR: a review of the challenges and approachesSemantic proximity Read ↗

CRISPR Technology in Disease Management: An Updated Review of Clinical Translation and Therapeutic Potential.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.