Article
Association of bone marrow fibrosis with inferior survival outcomes in chronic myelomonocytic leukemia.
Annals of hematology - 1 Jul 2018
Khan Maliha, Muzzafar Tariq, Kantarjian Hagop, Badar Ifra, Short Nicholas, Wang Xuemei, Chamoun Kamal, Jain Preetesh, DiNardo Courtney, Pemmaraju Naveen, Bose Prithviraj, Borthakur Gautam, Cortes Jorge, Verstovsek Srdan, Garcia-Manero Guillermo, Estrov Zeev
Abstract excerpt
The impact of bone marrow fibrosis grade on the prognosis of patients with chronic myelomonocytic leukemia (CMML) remains controversial. Therefore, we examined the records of 82 patients diagnosed with CMML at our institution and summarized baseline characteristics and molecular profiles by subgroups of absent or mild (grades 0/1) and moderate (grade 2) fibrosis. Cox proportional hazards models were constructed...
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