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Article

GAEC1 mutations and copy number aberration is associated with biological aggressiveness of colorectal cancer.

European journal of cell biology - 1 Apr 2018

Lee Katherine Ting-Wei, Gopalan Vinod, Islam Farhadul, Wahab Riajul, Mamoori Afraa, Lu Cu-Tai, Smith Robert Anthony, Lam Alfred King-Yin

Abstract excerpt

GAEC1 (gene amplified in oesophageal cancer 1) is a transforming oncogene with tumorigenic potential observed in both oesophageal squamous cell carcinoma and colorectal cancer. Nonetheless, there has been a lack of study done on this gene to understand how this gene exert its oncogenic properties in cancer. This study aims to identify novel mutation sites in GAEC1. To do so, seventy-nine matched colorectal...

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Identifiers

PMID: 29555101
DOI: 10.1016/j.ejcb.2018.03.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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