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The New and Advanced Cystic fibrosis transmembrane conductance regulators Modulators in Children with Cystic Fibrosis: A Narrative Review on Long-Term Outcomes, Recent Advances, and Comparative Insights.

2025-06-23

Abstract excerpt

Cystic fibrosis (CF) is a progressive, life-limiting genetic disorder caused by mutations in the CFTR gene, leading to dysfunctional chloride channels and multisystem involvement. The introduction of CFTR modulators has revolutionized CF management by targeting the underlying protein defect rather than just alleviating symptoms. These therapies such as Ivacaftor, Lumacaftor/Ivacaftor, Tezacaftor/Ivacaftor, and Tri...

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Literature Corpus work
a1bde5b9-568f-5ae7-90cc-c8a8d53a5035
DOI
10.22541/au.175065678.87130337/v1
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The New and Advanced Cystic fibrosis transmembrane conductance regulators Modulators in Children with Cystic Fibrosis: A Narrative Review on Long-Term Outcomes, Recent Advances, and Comparative Insights.DOI 10.22541/au.175065678.87130337/v1
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