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Article

Retention of functional variation despite extreme genomic erosion: MHC allelic repertoires in the Lynx genus.

BMC evolutionary biology - 4 Jul 2017

Marmesat Elena, Schmidt Krzysztof, Saveljev Alexander P, Seryodkin Ivan V, Godoy José A

Abstract excerpt

BACKGROUND: Demographic bottlenecks erode genetic diversity and may increase endangered species' extinction risk via decreased fitness and adaptive potential. The genetic status of species is generally assessed using neutral markers, whose dynamic can differ from that of functional variation due to selection. The MHC is a multigene family described as the most important genetic component of the mammalian immune...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28676046
DOI: 10.1186/s12862-017-1006-z
PMCID: PMC5496644

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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