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Article

Metastatic Site Location Influences the Diagnostic Accuracy of ctDNA EGFR- Mutation Testing in NSCLC Patients: a Pooled Analysis.

Current cancer drug targets - 1 Jan 2018

Passiglia Francesco, Rizzo Sergio, Rolfo Christian, Galvano Antonio, Bronte Enrico, Incorvaia Lorena, Listi Angela, Barraco Nadia, Castiglia Marta, Calo Valentina, Bazan Viviana, Russo Antonio

Abstract excerpt

BACKGROUND: Recent studies evaluated the diagnostic accuracy of circulating tumor DNA (ctDNA) analysis in the detection of epidermal growth factor receptor (EGFR) mutations from plasma of NSCLC patients, overall showing a high concordance as compared to standard tissue genotyping. However it is less clear if the location of metastatic site may influence the ability to identify EGFR mutations. OBJECTIVE: This...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29521235
DOI: 10.2174/1568009618666180308125110

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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