Article
The KCNQ1 gene polymorphism as a shared genetic risk for rheumatoid arthritis and chronic periodontitis in Japanese adults: A pilot case-control study.
Journal of periodontology - 1 Mar 2018
Kobayashi Tetsuo, Kido Jun-Ichi, Ishihara Yuichi, Omori Kazuhiro, Ito Satoshi, Matsuura Takato, Bando Takashi, Wada Jun, Murasawa Akira, Nakazono Kiyoshi, Mitani Akio, Takashiba Shogo, Nagata Toshihiko, Yoshie Hiromasa
Abstract excerpt
BACKGROUND: A number of studies have suggested a bidirectional relationship of periodontitis with rheumatoid arthritis (RA) and type 2 diabetes mellitus (T2DM). However, the genetic factors that underlie these relationships have not been elucidated. METHODS: We conducted a multicenter case-control study that included 185 patients with RA and chronic periodontitis (CP), 149 patients with T2DM and CP, 251 patients...
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