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Article

Pharmacogenetics of immunosuppressants: State of the art and clinical implementation - recommendations from the French National Network of Pharmacogenetics (RNPGx).

Therapie - 1 Apr 2017

Woillard Jean-Baptiste, Chouchana Laurent, Picard Nicolas, Loriot Marie-Anne

Abstract excerpt

Therapeutic drug monitoring is already widely used for immunosuppressive drugs due to their narrow therapeutic index. This article summarizes evidence reported in the literature regarding the pharmacogenetics of (i) immunosuppressive drugs used in transplantation and (ii) azathioprine used in chronic inflammatory bowel disease. The conditions of use of currently available major pharmacogenetic tests are detailed...

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Identifiers

PMID: 28318610
DOI: 10.1016/j.therap.2016.09.016

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