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Genomics of pyrrolnitrin biosynthetic loci: evidence for conservation and whole‐operon mobility within Gram‐negative bacteria

12 Sept 2008

Abstract excerpt

Pyrrolnitrin (PRN) is a tryptophan-derived secondary metabolite produced by a narrow range of gram-negative bacteria. The PRN biosynthesis by rhizobacteria presumably has a key role in their life strategies and in the biocontrol of plant diseases. The biosynthetic operon that encodes the pathway that converts tryptophan to PRN is composed of four genes, prnA through D, whose diversity, genomic context and spread...

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PMID: 18793314
DOI: 10.1111/j.1462-2920.2008.01750.x

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