Article
The orphan histidine kinase PdtaS-p regulates both morphological differentiation and antibiotic biosynthesis together with the orphan response regulator PdtaR-p in Streptomyces.
Microbiological research - 1 Mar 2020
Li Lei, Zhao Yawei, Ma Jingjing, Tao Hengnuo, Zheng Guosong, Chen Jun, Jiang Weihong, Lu Yinhua
Abstract excerpt
In Streptomyces pristinaespiralis, the orphan histidine kinase (HK) PdtaS-p (encoded by SSDG_02492), which belongs to proteins of two-component systems (TCSs), plays an important role in both morphological differentiation and antibiotic biosynthesis. Owing to the isolated genetic organization of pdtaS-p, it is a challenge to identify its cognate response regulator (RR) and hampers the efforts to elucidate the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.