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Article

MSR1 repeats modulate gene expression and affect risk of breast and prostate cancer.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 May 2018

Rose A M, Krishan A, Chakarova C F, Moya L, Chambers S K, Hollands M, Illingworth J C, Williams S M G, McCabe H E, Shah A Z, Palmer C N A, Chakravarti A, Berg J N, Batra J, Bhattacharya S S

Abstract excerpt

Background: MSR1 repeats are a 36-38 bp minisatellite element that have recently been implicated in the regulation of gene expression, through copy number variation (CNV). Patients and methods: Bioinformatic and experimental methods were used to assess the distribution of MSR1 across the genome, evaluate the regulatory potential of such elements and explore the role of MSR1 elements in cancer, particularly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29509840
DOI: 10.1093/annonc/mdy082

Genes

MSR1
KLK14

Provenance

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