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Development and Validation of a Novel RNA Sequencing–Based Prognostic Score for Acute Myeloid Leukemia

29 Jan 2018

Abstract excerpt

Background: Recent progress in sequencing technologies allows us to explore comprehensive genomic and transcriptomic information to improve the current European LeukemiaNet (ELN) system of acute myeloid leukemia (AML). Methods: We compared the prognostic value of traditional demographic and cytogenetic risk factors, genomic data in the form of somatic aberrations of 25 AML-relevant genes, and whole-transcriptome...

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PMID: 29506270
DOI: 10.1093/jnci/djy021

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