Article
Drug Resistance-Associated Mutations in Antiretroviral Treatment-Experienced Patients in Kuwait.
Medical principles and practice : international journal of the Kuwait University, Health Science Centre - 1 Jan 2018
Chehadeh Wassim, Albaksami Osama, John Sonia Elezebeth, Al-Nakib Widad
Abstract excerpt
OBJECTIVES: To investigate the prevalence of nonpolymorphic resistance-associated mutations (RAM) in HIV-1 patients on first-line antiretroviral therapy in Kuwait. SUBJECTS AND METHODS: Total RNA was isolated from plasma samples of 42 patients who received a first-line nonnucleoside reverse transcriptase inhibitor (NNRTI)-based regimen. HIV-1 protease and reverse transcriptase genetic regions were then amplified...
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