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Article

Existence and stability of periodic solutions of an impulsive differential equation and application to CD8 T-cell differentiation.

Journal of mathematical biology - 1 Jun 2018

Girel Simon, Crauste Fabien

Abstract excerpt

Unequal partitioning of the molecular content at cell division has been shown to be a source of heterogeneity in a cell population. We propose to model this phenomenon with the help of a scalar, nonlinear impulsive differential equation (IDE). To study the effect of molecular partitioning at cell division on the effector/memory cell-fate decision in a CD8 T-cell lineage, we study an IDE describing the...

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PMID: 29500513
DOI: 10.1007/s00285-018-1220-3

Genes

IDE

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