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Article

Impairment of memory generalization in preclinical autosomal dominant Alzheimer's disease mutation carriers.

Neurobiology of aging - 1 May 2018

Petok Jessica R, Myers Catherine E, Pa Judy, Hobel Zachary, Wharton David M, Medina Luis D, Casado Maria, Coppola Giovanni, Gluck Mark A, Ringman John M

Abstract excerpt

Fast, inexpensive, and noninvasive identification of Alzheimer's disease (AD) before clinical symptoms emerge would augment our ability to intervene early in the disease. Individuals with fully penetrant genetic mutations causing autosomal dominant Alzheimer's disease (ADAD) are essentially certain to develop the disease, providing a unique opportunity to examine biomarkers during the preclinical stage. Using a...

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Identifiers

PMID: 29494861
DOI: 10.1016/j.neurobiolaging.2018.01.022
PMCID: PMC5871602

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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