Article
Genetic Polymorphisms of Glucose-6-Phosphate Dehydrogenase in Lagos, Nigeria.
Hemoglobin - 1 Jan 2018
Babalola Musa O, Imaga Ngozi A, Samuel Titilola A, Diriwari Iyanu P, Kolade Olajumoke, Ezeamalu Irene, Laoye Adefioye O, Ojewunmi Oyesola O
Abstract excerpt
Glucose-6-phosphate dehydrogenase (G6PD) is an essential enzyme in the pentose phosphate pathway that prevents oxidative damage to cells. This study determined the genotypic and allelic frequencies of G6PD G202A and A376G and also investigated correlation between G6PD polymorphisms and hemoglobin (Hb) phenotypes in children in Lagos, Nigeria. Seventy-eight children [55 with Hb AA (βΑ/βA) and 23 with Hb AS (βΑ/βS)...
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