Article
Haematological values in homozygous sickle cell disease in steady state and haemoglobin phenotypes AA controls in Lagos, Nigeria.
BMC research notes - 1 Aug 2012
Akinbami Akinsegun, Dosunmu Adedoyin, Adediran Adewumi, Oshinaike Olajumoke, Adebola Phillip, Arogundade Olanrewaju
Abstract excerpt
BACKGROUND: Sickle cell disease is a genetic abnormality involving the haemoglobin. Although, it is primarily a red cell disorders, the white blood cells and platelets are also affected by the mutation. The consequent haemoglobin S causes polymerization of haemoglobin resulting in haemolysis and anaemia. This study aims to provide baseline haematological values in sickle cell disease patients in steady state and...
Topics
- Adult
- Anemia
- Anemia, Sickle Cell
- Blood Cell Count
- Case-Control Studies
- Demography
- Female
- Hemoglobin A
- Homozygote
- Humans
- Male