Article
Haematological values in homozygous sickle cell disease in steady state and haemoglobin phenotypes AA controls in Lagos, Nigeria.
BMC research notes - 1 Aug 2012
Akinbami Akinsegun, Dosunmu Adedoyin, Adediran Adewumi, Oshinaike Olajumoke, Adebola Phillip, Arogundade Olanrewaju
Abstract excerpt
BACKGROUND: Sickle cell disease is a genetic abnormality involving the haemoglobin. Although, it is primarily a red cell disorders, the white blood cells and platelets are also affected by the mutation. The consequent haemoglobin S causes polymerization of haemoglobin resulting in haemolysis and anaemia. This study aims to provide baseline haematological values in sickle cell disease patients in steady state and...
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