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Diagnostic performance of metagenomic next-generation sequencing among hematological malignancy patients with bloodstream infections after antimicrobial therapy

27 Dec 2024

Abstract excerpt

BACKGROUND: Metagenomic next-generation sequencing (mNGS) is an effective method for detecting pathogenic pathogens of bloodstream infection (BSI). However, there is no consensus on whether the use of antibiotics affects the diagnostic performance of mNGS. We conducted a prospective clinical study aiming to evaluate the effect of antimicrobial treatment on mNGS. METHODS: Blood samples were collected for mNGS...

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PMID: 39733825
DOI: 10.1016/j.jinf.2024.106395

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