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Article

Single cell polarity in liquid phase facilitates tumour metastasis

22 Feb 2018

Abstract excerpt

Dynamic polarisation of tumour cells is essential for metastasis. While the role of polarisation during dedifferentiation and migration is well established, polarisation of metastasising tumour cells during phases of detachment has not been investigated. Here we identify and characterise a type of polarisation maintained by single cells in liquid phase termed single-cell (sc) polarity and investigate its role...

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PMID: 29491397
DOI: 10.1038/s41467-018-03139-6

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