Article
Loss of ARID1A Expression Correlates With Tumor Differentiation and Tumor Progression Stage in Pancreatic Ductal Adenocarcinoma.
Technology in cancer research & treatment - 1 Jan 2018
Zhang Li, Wang Cuiping, Yu Shuangni, Jia Congwei, Yan Jie, Lu Zhaohui, Chen Jie
Abstract excerpt
Mutations in the AT-rich interactive domain 1A gene, which encodes a subunit of the Switch/Sucrose nonfermentable chromatin remodeling complex, can result in loss of protein expression and are associated with different cancers. Here, we used immunohistochemistry to investigate the significance of AT-rich interactive domain 1A loss in 73 pancreatic ductal adenocarcinoma cases with paired paracancerous normal...
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