Article
Genome profiling of pancreatic adenocarcinoma.
Genes, chromosomes & cancer - 1 Jun 2011
Birnbaum David J, Adélaïde José, Mamessier Emilie, Finetti Pascal, Lagarde Arnaud, Monges Geneviève, Viret Frédéric, Gonçalvès Anthony, Turrini Olivier, Delpero Jean-Robert, Iovanna Juan, Giovannini Marc, Birnbaum Daniel, Chaffanet Max
Abstract excerpt
Pancreatic adenocarcinoma is one of the most aggressive human cancers. It displays many different chromosomal abnormalities and mutations. By using 244 K high-resolution array-comparative genomic hybridization (aCGH) we studied the genome alterations of 39 fine-needle aspirations from pancreatic adenocarcinoma and eight human adenocarcinoma pancreatic cell lines. Using both visual inspection and GISTIC analysis,...
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