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Article

Mathematical modelling of the antibiotic-induced morphological transition of Pseudomonas aeruginosa.

PLoS computational biology - 1 Feb 2018

Spalding Chloe, Keen Emma, Smith David J, Krachler Anne-Marie, Jabbari Sara

Abstract excerpt

Here we formulate a mechanistic mathematical model to describe the growth dynamics of P. aeruginosa in the presence of the β-lactam antibiotic meropenem. The model is mechanistic in the sense that carrying capacity is taken into account through the dynamics of nutrient availability rather than via logistic growth. In accordance with our experimental results we incorporate a sub-population of cells, differing in...

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Identifiers

PMID: 29481562
DOI: 10.1371/journal.pcbi.1006012
PMCID: PMC5843380

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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