Article
Evolution of SUMO Function and Chain Formation in Insects.
Molecular biology and evolution - 1 Feb 2016
Ureña Enric, Pirone Lucia, Chafino Silvia, Pérez Coralia, Sutherland James D, Lang Valérie, Rodriguez Manuel S, Lopitz-Otsoa Fernando, Blanco Francisco J, Barrio Rosa, Martín David
Abstract excerpt
SUMOylation, the covalent binding of Small Ubiquitin-like Modifier (SUMO) to target proteins, is a posttranslational modification that regulates critical cellular processes in eukaryotes. In insects, SUMOylation has been studied in holometabolous species, particularly in the dipteran Drosophila melanogaster, which contains a single SUMO gene (smt3). This has led to the assumption that insects contain a single...
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