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Expression and function of immune ligand-receptor pairs in NK cells and cancer stem cells: therapeutic implications

22 Feb 2018

Abstract excerpt

BACKGROUND: The interplay between the immune system and cancer cells has come to the forefront of cancer therapeutics, with novel immune blockade inhibitors being approved for the treatment of an increasing list of cancers. However, the majority of cancer patients still display or develop resistance to these promising drugs. It is possible that cancer stem cells (CSCs) are contributing to this therapeutic...

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PMID: 29470831
DOI: 10.1007/s13402-018-0373-9

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