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Article

Different qualifiers of AUS/FLUS thyroid FNA have distinct BRAF, RAS, RET/PTC, and PAX8/PPARg alterations.

Cancer cytopathology - 1 May 2018

Bellevicine Claudio, Sgariglia Roberta, Migliatico Ilaria, Vigliar Elena, D'Anna Melania, Nacchio Maria Antonia, Serra Nicola, Malapelle Umberto, Bongiovanni Massimo, Troncone Giancarlo

Abstract excerpt

BACKGROUND: The Bethesda System for Reporting Thyroid Cytopathology category of atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) includes fine-needle aspiration (FNA) specimens that cannot straightforwardly be classified as benign or malignant. To determine whether morphological subcategorization based on atypia qualifiers and molecular testing could improve malignancy...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29469940
DOI: 10.1002/cncy.21984

Genes

BRAF
PAX8
RET
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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