Article
Thyroid "atypia of undetermined significance" with nuclear atypia has high rates of malignancy and BRAF mutation.
Cancer cytopathology - 1 Jul 2014
Park Hyo Jin, Moon Jae Hoon, Yom Cha Kyong, Kim Kyu Hyung, Choi June Young, Choi Sang Il, Ahn Soon-Hyun, Jeong Woo-Jin, Lee Won Woo, Park So Yeon
Abstract excerpt
BACKGROUND: "Atypia of undetermined significance" (AUS) in the Bethesda System for Reporting Thyroid Cytopathology is a heterogeneous category for cases that cannot be easily classified into benign, suspicious, or malignant. This study evaluated whether cytomorphology-based subcategorization could better predict the malignancy risk in cases designated as AUS, and how the subcategories correlated with BRAF...
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