Article
Furfural-tolerant Zymomonas mobilis derived from error-prone PCR-based whole genome shuffling and their tolerant mechanism.
Applied microbiology and biotechnology - 1 Apr 2018
Huang Suzhen, Xue Tingli, Wang Zhiquan, Ma Yuanyuan, He Xueting, Hong Jiefang, Zou Shaolan, Song Hao, Zhang Minhua
Abstract excerpt
Furfural-tolerant strain is essential for the fermentative production of biofuels or chemicals from lignocellulosic biomass. In this study, Zymomonas mobilis CP4 was for the first time subjected to error-prone PCR-based whole genome shuffling, and the resulting mutants F211 and F27 that could tolerate 3 g/L furfural were obtained. The mutant F211 under various furfural stress conditions could rapidly grow when...
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