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Article

Dissecting a complex chemical stress: chemogenomic profiling of plant hydrolysates.

Molecular systems biology - 18 Jun 2013

Skerker Jeffrey M, Leon Dacia, Price Morgan N, Mar Jordan S, Tarjan Daniel R, Wetmore Kelly M, Deutschbauer Adam M, Baumohl Jason K, Bauer Stefan, Ibáñez Ana B, Mitchell Valerie D, Wu Cindy H, Hu Ping, Hazen Terry, Arkin Adam P

Abstract excerpt

The efficient production of biofuels from cellulosic feedstocks will require the efficient fermentation of the sugars in hydrolyzed plant material. Unfortunately, plant hydrolysates also contain many compounds that inhibit microbial growth and fermentation. We used DNA-barcoded mutant libraries to identify genes that are important for hydrolysate tolerance in both Zymomonas mobilis (44 genes) and Saccharomyces...

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Identifiers

PMID: 23774757
DOI: 10.1038/msb.2013.30
PMCID: PMC3964314

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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